Dr Ali KILIC

Paris 06-05-2008

The Academy of the Sciences of Kurdistan
and
 The Physical Sciences,The Chemical and Biological Sciences,
And
The conference of the Academy of Sciences in Paris

 



              The Physical Sciences, the  Chemical and Biological  Sciences were the subject of our analysis on the classification of Sciences[1] and Informatics, philosophical foundations of science. The philosophy of biology, chemistry and physics was one of my concerns in the history of science that led to the drafting of a project for the Foundation of the Academy of Sciences of Kurdistan, in the but the planning and scheduling of science for the founding of the State of the Republic of Kurdistan. But Mr Massoud Barzani and Mr Talabani Djelal have not responded to our request.


            On 13 May 2008 the section of molecular and cellular biology, genomics of the Academy of Sciences will organize a conference on epigenetics and cellular memory. This is a new discipline of molecular and cellular biology, genomics. The question that arises What is epigenetics? What is the relationship established with scientific research that I had completed twenty years ago? What are the conclusions in relation to the project for the founding of the Academy of Kurdistan that we introduced since January 2005 the authorities of Kurdistan?

               Indeed, for researchers and scientists of Kurdistan where the Foundation of the Academy of Sciences and the Center of the Research Scientifical   of Kurdistan, is a question of the organization's scientific knowledge, it is now our hearts scientific and philosophical works for years. The question that arises is: how Scientific Kurdistan can remain indifferent face of scientific and technical progress insofar States which occupy Kurdistan use all the new technologies to prevent the release of the Kurdish people. In other words, how and by what means our researchers can transform these new technologies to change the relationship of forces so that scientific and technological progress is available to the construction of Kurdistan released. There are several reasons.

           First scientific reason for organising the science and objective of the Academy of Sciences. With the scientific and technological revolution, the radical qualitative performed in the modern system of science change all aspects of technological and reports highlight the important scientific tasks and complex: Substantial, because they require the need to discard the scientific basis of a new society through the introduction of new technologies. Because the Scientific and Technical Revolution have created a new rule of Science and Technology
.

that the technology on the production, science becomes a decisive factor and more dynamic development of productive forces. Complexes, because "the times they are essential to maintain the competitiveness of the economy in crisis, and both create antagonistic contradictions which" have changes in technology, knowledge about man in his life, on employment must be drastically controlled. "

Nowadays, nobody questioned the fact that science can serve humanity, mankind and all peoples of the world, but at the same time, we find that its results are often used by dominant forces for humanity and harming the interests of peoples. This situation creates a serious social problem;

How to give, Scientific guidance which will promote the development of civilization?
How to learn to control the movement of scientific thought in line with the interests of man, of humanity and peoples?

In both cases, the question that arises in the first place, concerns the organization of science in society and scientific research, forecasting the development of social processes and in science itself. These applications of science and science that highlight the principles of Ethics of Science, which became the subject of numerous scientific research. The truth is that the study of science, is a necessity in scientific reality of our time in the history of philosophy, the issue of science, has been asked by philosophers in two ways:

Firstly, science is a cognitive activity.  Secondly, science is a system of knowledge of the man with an object and a method of investigation own. This requires the active intervention of the organization's scientific knowledge of employees for a new scientific planning and organization of a new division of scientific work to found the Academy of Sciences of Kurdistan. Based on a dialectic of Sciences classification based on the division des Sciences de l'Homme, Natural Sciences and Earth Sciences and space, the Academy of Sciences sets its goal as follows:


_Adopter Of scientific research programmes of action to strengthen the role of science and increase the scientific and technical knowledge from a classification dialectic of science and interdisciplinary scientific interaction,

• carry out or have to carry out scientific research for the advancement of science, solve new problems or untreated until now in the fields of Anatolian Civilizations, to help safeguard crops millennia

• encourage researchers to do work, subsidize scientific publications and create new units applied research to promote dialogue between scientific activities and the opening of an international scientific and technical cooperation,

• organize and monitor the preparatory education to research. Ultimately, the objectives of the scientific approach of the organization of scientific knowledge is to answer questions from the scientific environment and highlight the scientific research units and the links between them.

The study of the scientific environment


1. What scientific environment are we?


2. What is the scientific potential exists inside and outside the country and what is the level of its scientific organization, technical and academic?


3. What are qualities existing scientific and scientific purpose for which we can reorganize the scientific needs of the country and the region and how we can improve performance in the four Universities of Kurdistan?


4. What are the prospects for an opening for international scientific and technical cooperation for a scientific organization and basic research in considering the challenges and risks?
5. What is our strategic choice and technology in relation to the scientific purpose, political, commercial and how can we develop new methods using new technologies from the organization of scientific knowledge and its international transfer in the process the founding of Kurdish state and facing the development of European science?


5. Structures of the organization's scientific knowledge


A) The organization of scientific knowledge in organizing the scientific potential existing in Kurdistan and Mesopotamia


B) The nature of the organization and planning and reorganization of science in the process of creating Constituent Assembly and the state in South Kurdistan.



C) The definition of scientific and technical tasks main and sub-specialized scientific tasks for the planning of the Society of Kurdistan,


Finally, the search is a scientific activity whose purpose is scientific practice.

• The completion of a scientific research is carried out by a methodology which is either a technical procedure, either a strategy for the scientific purpose or carrying out several tasks. This means that the completion of each task requires the active participation of every scientist specialized in light of data on which apply the scientific objective determined.

The free choice of the researcher and scientist is the foundation of development and the development of scientific freedom and academic researcher or scientist is responsible for its choice and the appropriate method in the sector and is obliged to carry out scientific, technical and artistic accordance with its choices.


6. The current direction of science and the scientific purpose of the dissemination of science for a real scientific methodology of the theoretical analysis of the organization of scientific knowledge requires determining the direction of development of science and the study their application areas. In this sense, we believe it is impossible to resolve the issues of reorganization of scientific knowledge and its links with the company is asking these questions in human sciences is a science of nature, as matters purely methodological, which totally disregards the qualities gnoséological  or as purely gnoséological  which are totally ignored methodological issues of knowledge and science (ignore the dialectic), either as purely economic issues and policies which completely ignore the application of science to production. On the other hand, it means that the strict application of science to production is a necessity, because the needs of society are composed of the needs of science, whose satisfaction will depend mainly on the level of production, the state of technical, material possibilities and potential scientific society itself. The focus of our scientific approach to the founding of the Centre de la Recherche Scientifique of Kurdistan depends primarily on the reorganization of the human sciences of the natural sciences and earth sciences and space in second place the interpretation of the purpose of basic and applied sciences. That is why we attach great value to science academies of sciences in Europe, especially at the Academy of Sciences of France including the foundations of the founding of the Academy of Sciences of Kurdistan.

What is the relationship established between our scientific and academic level of development of science and the Conference of the Academy of Sciences after twenty years of our scientific and academic work?


The key issue is that the development of physical sciences. Chemical
and biological basis of the diversification of scientific branches of science was my point of departure.

First I pay tribute to the President of Academic and Scientific Jury who spoke favorably upon presentation of my thesis. "Lovers traces of surfaces, images of body movement remarkable connoisseur of the arts of science[2] and technology" François Dagognet in his speech at the Symposium of Creusot, said "science has not ceased to lay out what is l 'Interiority. The disciplines most innovative operators have pulled their procedures secret, then broken. reproduced and even improved It has suffered from this kidnapping. was. challenged, but he did so far interrupted.. "[3]But the problem is how one of the major development of science is that it is oriented towards the study not only of items already Included in the transformation practice of the mass. production, in everyday experience. Mats also objects whose use practice will in principle only to future stages of historical development. civilization as a whole?

In the course of its history, science equated various types of objects systemic, developing knowledge on their properties, on the laws of their operation and transformation.

Each type of organization requires systemic objects to be known and understood, a special category grid serving concrete scientific notions that characterize the details of the structure and behaviour of objects in question.

Undoubtedly philosophy is capable of creating categorical matrices necessary for scientific research before the science begins to control the types of matching. The application categories developed by philosophy in scientific research concrete enriches and develops it. However, to fix their content again, we need once again to. Reflection on the philosophical science that form a particular aspect of philosophical apprehension of reality in the course do which is developing the device block of philosophy. "But the philosophy is not a science. (.) Its purpose is not this or that particular area of reality. But at the same time philosophy is a science-science general laws of reality.. Here, E. Bitsakis[4] mixing the definition of the dialectic with philosophy. It is distinct and special science is at the same time a science for many reasons he says. "The philosophy has an object; it seeks to identify and formulate laws on this subject: She uses the methods of science. It has a body of knowledge, it has a history, as science-like and at the same time profoundly different ;(...) File The definition of philosophy as science can not conceal its specific character, its relative autonomy by special report on science and its qualitative difference compared to them. The formula science and defines the concepts, philosophy and formula defines the philosophical categories.. "La. confrontation in the history of philosophy[5] and natural sciences can therefore see that philosophy has certain possibilities projected in relation to scientific research, since it is capable of producing in advance categorical structures that will be necessary . "Philosophy can not play its effective role in developing the design of world scientific writing N, Séménov, if it manages to be argued along with other sciences, as their equal, ie as Science special issue with its precise, a litigant also meticulous study and concrete that the object of any science, "[6](3). The contradiction between itself the universal character of human knowledge and his approach necessarily compartmentalized within science, the contradiction between the specification of scientific knowledge and the trend towards integration, that's what makes it so indispensable development d 'A world-scientific' philosophy.


The question that arises is what are the mechanisms to ensure such a development class development of science of unity and diversification of their branches of science in general and scientific development of information technology in particular. The answer is not related only to study the nature of philosophical knowledge but also the knowledge engineering. It involves analysis function of philosophy as a theoretical kernel of the design world and the cognitive activity of the elucidation of the relationship between philosophical categories and the culture.

The science, scientific and technological revolution have led to deep differences between the various branches specializing in the manufacture of products. But gradually as the growing differentiation and that there always new branches. We see the growing importance of relations between the various branches and their coordination, which call for a centralized function of the economy. At the heart of this scientific development instead of science applied to. all levels of life is crucial. That is why it is necessary to clarify our classification dialectic of science and the place of information technology in the scheme we are proposing is a characteristic of science.


First, the classification dialectic of basic sciences division between the natural sciences and human sciences and finally the technical sciences. Then we divide the natural sciences into three parts:


1. The physical and technical sciences and mathematics
2.The science-technology chemical and biological

 _____
3. The Earth Sciences.

L The physical and technical sciences and mathematics
divided into six parts: They are:

I. scientific computing and automation
2. The mathematics
3. The general physics and astronomy
4. Nuclear physics
5. The physical technique of energy
6. The mechanical and ordering process

II. Science chemical-and biological technology are divided into five parts:

L. The general chemistry and technical
2. La. Physico-chemistry and technology of inorganic substances
3. The biochemistry, biophysics and chemical compounds,
4. The physiology
5. The general biology.

111. 1st earth sciences are es following:

1 The geology, geochemistry and geophysics
2. The oceanography, physics of 1 atmosphere


The human sciences are divided between:

I. The philosophy
2. The story
3. 1 economy and the law
4. literature and linguistics.

The development of science was determined by three basic sciences: the physical sciences, chemical sciences and biological sciences. The classification of science and the connection and differentiation of branches scientific computing are inseparable from the scientific process.


I. The physical sciences

They are undoubtedly physics and physicists who kicked off the revolution in the natural sciences of our time. The funky and discoveries, the rapid development of physical sciences, particularly after the Second World War, have fertilized and stimulated the development and progress radicals other natural sciences.

The inevitable intervention of physics in all divisions of science proceeds in large measure because , takes as subject to study the properties of both the simplest and most general of terms. This is a good reason that physics is called the "mother of. Mechanics. " The progress of physical sciences exerts a direct influence on all the essential elements of modern production - energy base, working tools and technology physics exerts a strong influence on objects of work (and raw materials). This is particularly evident in our time where we see the rise of energy and atomic and nuclear technology, electronic technology and laser technology semiconductors and integrated circuits.

One can say without exaggeration that the results of the physical sciences o. served as a starting point for the creation and development of a very large number basic sciences (particularly those that arise at the junction of chemical and physical sciences, biological and physical). and many fundamental scientific disciplines of engineering.

The progress of physics have exerted a huge influence on the design of the contemporary world. This is due primarily to the close links uniting physics and. theory of knowledge, Divisions fundamental modern physics, as the study of the structure of matter theory. a relativity, quantum mechanics, are organically linked to the theory of knowledge.

The restricted theory of widespread. Relativity of Albert Einstein's theory of e la, quantum mechanics were naturally fundamental theories that have given the departure of scientific theory and modern physics for a large part in all the natural sciences.

In contemporary science, Einstein's scientific work, provide a striking example. It proves that the relativity of space, time and movement, one can infer that the mass of a body depends on its speed and thus energy movement. If the speed approaching its limit - 300 000 km / sec - the mass of the body tends to infinity, La. Thesis Einstein that mass of a body at rest depends on its internal energy E had an immense importance. The pier and was the basis of the energy of the scientific revolution.

and technical It appeared that if we measured the energy and mass through the normal units, energy is equal to mass multiplied by the square of the speed of light -1. In other words E. = ml

The division of the nucleus of uranium reached 3 million times more energy than the chemical reaction of a combustion (1g uranium provides more heat than 3 tons of coal). But it is there. That a small portion of the energy contained in all the mass of matter. Already nuclear energy uses about ten times more than the inner energy particles compared with Atomic Energy of the disintegration of heavy nuclei.

The formula Einstein opens up prospects even more remote and grandiose energy use kernel, it contains the following steps of the scientific and technological revolution in the energy field. To get a complete picture of potential energy of matter flowing from the formula of Einstein, just engaging â, simple arithmetic.


According to Einstein's formula, energy is equal to the mass (say, for example 1g) multiplied by the square of the speed of light -1. The speed of light is 300 000 km / s, or 3.10 cm / s. Consequence 1 = 9.10 cm / s. By multiplying the mass in grams per 1 we get the energy it contains ergs. 1kWh is equal to. 3,6.10 ergs. So the total energy recelée in one gram of substance is equal to 9.10 ergs, and divided by 3,6.10, it is equal to 2.5.10 kWh (or 25 million kwh).

From the reactions that we are known today, the full realization of this energy is possible only through the clash of matter and antimatter, called by the reaction of annihilation. It was determined that if a particle meets its corresponding antiparticle, they annihilate disappear, while their energy and mass are converted into energy and more full (for example in the radiation), without breaking the law of the conservation, with full realization of all energy, according to Einstein's formula E = ml This exceeds several thousand times the amount of energy per unit mass reached at the nuclear reactions,

The revolution in physics has therefore opportunities for turning in technique and in any material production.

Another axis of the scientific revolution in physics, closely related. nuclear physics and the atomic energy quantum mechanics, heralds a turning revolutionary technology, technology and production.

One can understand the processes leading to fission and nuclear synthesis only, using the theory of quanta. Quantum mechanics was the theoretical basis for development of electronics, and later, generators quantum of light, lasers, ie the fundamental basis of a revolutionary turning already visible in production technology.

The opportunities afforded by the use of laser beams are immense.

The properties of laser-the opportunity to focus on tiny masses of matter-permit, the leader on a mass thermonuclear (a mixture of deuterium and tritium), to create the conditions for a thermonuclear reaction temperature of tens of millions of degrees and density of fuel exceeding hundreds of times the density of the solid body. This is a promising direction of establishing a thermonuclear energy.

The application of laser technology also opens up great prospects. the creation of a method of optical information processing and manufacturing of optical calculators speed operative - known as optoelectronics. This involves replacing a liaison usual cable and wire by an optical link - a light-guide fiber, the manufacture of a 'working optical memory of a great capacity for computers and a' memory) Permanent for information systems.


All these ideas and. Discoveries have opened the door has an extraordinary progress of the radio and the procession triomphai of l1ectronique that penetrates literally touti'4es branches of the art and areas of technology.

The influence that physics, including quantum theory, has exercised over the chemical sciences, is. this respect very instructive. The classification periodic Mendêléev, which was in large measure an empirical law of chemistry, has acquired, with the development. of quantum mechanics and approval model atomic quantum solid theoretical basis, fi is that the arrangement of elements discovered by Mendéléev a physical sense. both important and simple. The serial number of an element in the sense mendéléevien (physicists call it atomic number) is equal to the number of positive charges or, in other words, the number of protons in the nucleus of atoms of this element. The law Mendéléev became one of the laws of atomic physics and nuclear.
The quantum theory opens up tremendous opportunities to the physics of solid in the field of action on the fundamental properties of metals and crystal in general. The quantum properties of solids can use the crystal in the manufacture of many instruments of physics. The study of physical phenomena on thin semiconductor films has become an essential element of work to get integrated circuits, hybrid and functional, which directly affects. miniaturization and the microminiaturisation of electronic assemblies and the creation of the last generations of computers.

This is the table although incomplete decisive changes in the physical XXÔ century. All we have to say concerns scientific discoveries already. made and their impact already. Visible on the technical and material production,

But the revolution in physics continues. The technical means always the most powerful available for research in physics dice continually increasing its possibilities. With a technical research and experimentation increasingly complex, physicists, penetrating into the depths of the micro and macro world, discover new problems and not always resolved in a comprehensive and fundamental importance.

The successes in the construction of particle accelerators. energy growing yielded very important data which have raised fundamental problems whose solution will open at. humanity new opportunities.

These are primarily the problems of the structure of particles with a strong interaction (adrons), whose most famous are the proton and the neutron. Their properties and their systematic today are well described. from the assumption subélémentaires particles, quarks ...


It is quite possible that the energy obtained with the current accelerators is not sufficient to free quarks concentrated in adrons. If this hypothesis is confirmed, it means it will consider alternate methods of energy in the act Basic hundreds or thousands of doing more powerful than that achieved with conventional nuclear reactions, this opens the prospect of a gigantic leap in the potential energy of the universe and perhaps of mankind.

Another group again, that the problems of. weak interaction. He may have a fundamental importance not only to understand the microstructure of the material, but also the spatial and temporal structure of our world and, perhaps, for cosmology. In particular, it may be that the solution of major problems with the structure of. Matters will require fundamental review representations of space and time, that penetration in the heart of the micro-world make it possible processes which we now seem improbable I ".

In the opinion of physicists, approximation of particles at a distance of 10 - 16 - 10 - 17 cm may give rise to phenomena of fundamental importance. The distances that order correspond to an energy of about 300 billion électrovolts in a system whose center of inertia is a particle collision. That is why the study of a package to obtain protons to an energy of 2 to 5 trillion électrovolts.
And new opportunities hitherto unknown yet appear 'clash of heavy nuclei may give rise to phenomena comparable to the shock waves through the action which the nuclear material can go to unusual statements. The scientific researchers report in this regard the possible existence of new forms of nuclear material different from atomic nuclei that we know.

The acceleration of technology creates new phenomena practices purely technological and scientific. Here are some examples:

The beams of particles accelerated exerted on many substances very specific that we can not achieve by other methods,

sources of gamma rays, electronic accelerators are widely used for sterilization in the medical devices industry for the polymerisation radiation insulation cables, for défectoscopie large parts in the mechanical industry, etc..;beams of electrons with an intensity of up to one million amps are used in research to control thermonuclear fusion;

The accelerated heavy ions can be used in the manufacture of molecular filters virus by irradiation of a plastic film These filters can carry out disinfection of water by simple filtering.

These examples that we cited in the field of physics can lead to a new interpretation of the natural sciences and general laws of the world, open new prospects for the new technology and computerization of society and production This revolution in the physical sciences is inseparable in the chemical sciences in the unit dialectical process of scientific knowledge and technical. their applications.

11. The  Chemical Sciences

The revolution in science has developed chemical on one side of autonomously within the framework of this science, ie in the process of unification and diversification of chemical sciences, and the other, under the power of recent trends in physics and foremost in quantum physics, nuclear physics or high-energy subatomic physics.

The technical revolution in chemistry is linked to control of the structure of molecules and consequently the creation of substances structure and properties defined in advance, ie the creation of controlled chemical bonds. Again, integration (or interaction) and usage (differentiation) of recent concepts of physical sciences play a leading role. On the one hand, the scientific application of the architecture of molecules was followed by basic discoveries that, for example, who identified and molecular weight. validation of the notion of valence elements, ie the number of atoms types with which an atom of the element is able to unite to form a stable combination. Thus were made laws of the composition of molecules and laid the theoretical basis for chemical synthesis on the subject. On the other hand, the progress made by science chemical itself is taking advantage of new theories and possibilities offered by scientific branches of modern physics, which brings the first theoretical explanation of the many laws established empirically.

That said, the development of science around the middle of the twentieth century has revealed that not only the electron moving creates a magnetic field but that the electron at rest, also a "magnet Basic has a set of properties that allow it to be valentiel, The role of the electron results in a whole range of phenomena in the remarkable. Chemistry crystals, including control of a crystal lattice, inspecting properties semi-conductor and dielectric, the formation of entirely new chemical compounds.
 
The possibility to form molecules and substances naturally required to continue the study of architecture substances and existing molecules, its interrelation with the essential properties of the substance, as well as find ways to act on 'Architecture of molecules. It was intensely studied architecture at this great architect that nature. The essential properties of the material depending on the geometric layout of the same atoms in space (as part of molecules) gave birth to a specific branch of chemistry that deals with the spatial arrangement of atoms in the molecule and the influence of this factor on the geometric properties of matter is the stereochemistry. The emergence of this science was already provided for in the last century by A. Bourtherov,

That is why we can ask clearly explain the nature of the diversification of branches of science (physical, chemical, biological) in both the dialectical unity of fundamental interaction and diversity of unity and fight for their ? In other words, if the full knowledge of the structure and laws of the surrounding world has offered to humanity, technology and production, the possibility of creating a controlled and planned, substances and materials with properties defined in advance and necessary to men, is that there will be a scientific answer that will resolve the problem of labour computerized objects - one of the basic elements essential for material production assisted by new technology " ?

First, gasoline and specificity of the scientific and technological revolution are expressed in the combination of analysis and explanation of the structure of matter, the nature of reactions and processes that occur in the world surrounding the structure of the process of organic life, functioning mechanisms and the mechanical action on the process of working with processes of a whole. other order as:

-- Action-oriented structure of matter on the synthesis of body properties data in advance on obtaining artificial and monitoring reactions of disintegration and synthesis of light and heavy nuclei;

-- The development and practical use of an information theory, a theory and practice of automatic control systems, machines;

-- The creation of systems for automated data processing, management systems and automated automatic in the complex technical and socio-economic production;
-- A second action-oriented process of organic life ever more important.
The characteristics of a material and technical background. Revolution scientific computing with the corollary, the radical changes in relations between man and the environment, define the social aspect of this revolution. It does not affect only the technical and information technology in particular, but it also creates conditions for a radical change in the nature and content of human work in the technological processes in general. Besides, it radically changed the role of man and the role of science-kid in the system of productive forces.

A far-reaching social consequences of scientific and technological revolution is what a kid time offers the possibility to increase significantly the free time, which in turn creates conditions for an increase in the level of education and qualification. LifeIntellectual men is also profoundly changed they receive a mass and a range of information constantly growing, modern means of transport and communications so extraordinary increase their opportunities to participate in events as varied referring to times or to the most varied, the usual range of consumer goods and services change radically, leading to a change corollary of human needs. All these changes are marked by an extraordinary dynamism of social development.

Thus, the scientific revolution creates the physical premises of a development of productive forces, an increase of scientific potential that gives man's disposal the creative possibilities that allow it to intervene to modify and solve social problems Economic essential mode of production. Another exceptionally important premise of the revolution in the natural sciences is the intervention of mathematics and mathematical method in all fields of science. The formulation of the basic laws of physics, chemistry, biology and computer science today is based on mathematics. It is this reality that we want to develop the progress of theoretical chemistry, using the results of physics which have considerably broadened the range of problems studied by the chemical sciences. Car chemistry encompasses areas of the world always new organic and inorganic entering the field of science related form of new sciences boundary. S'enrichissant methods and conclusions of these sciences, while enriching them to the nth time, we want to include the basic guidelines of chemistry.

In a first step, we divide the general chemistry into two fundamental parts of the élémento-organic chemistry and the non-organic chemistry. In a second step, we will explore the diversification of scientific branches of chemistry and we want to show the possibility of this distinction in the existing system of science. The complex chemical compounds, geo-chemistry and chemistry of the earth, physical and chemical mechanical, electrochemistry, biochemistry, radio-chemistry, chemical physics, chemical kinetics, and to complete the chemistry of solid and agrochemicals. Then we will show the one hand, in developing the chemistry of solid, the problems of chemical classifications of these solids, and secondly, the method of molecular stratification created by researchers of our time, which contributed not only to the development of physical sciences, but also the progress made by the chemical sciences pursue their turn, a huge influence on the truly revolutionary developments taking place in biological sciences ..


The development of chemical sciences and classification of branches of science:


a) The élémento-organic chemistry, which is a junction of organic chemistry and non-organic The development of this branch has helped create entire families of new polymers organometallic compounds and organic properties still unknown, and d ' adopting technological methods for obtaining polymers incomparably easier and more economical.

b) The chemical compounds complexas who will discover many new classes of chemical compounds. She helped create one. Precious metals industry and solve the chemical aspects of nuclear energy, chemical compounds complex plays a crucial role with regard to the development of chemical processes effective technology for treating raw materials .*

c) The geochemistry or chemistry of the Earth, which in its research materials and Earth processes based on laws and chemical methods. This science studies the chemical evolution of our planet, seeks to explain the viewpoint chemical origin and history of the Earth, its layers, its terrain, mountains, seas and oceans.


d). physico-chemical mechanical linking the mechanical and electrical properties of matter at. its composition and chemical structure.

e) electrochemistry, branch of chemistry devoted to the study of the properties of ions containing systems and processes involving ions, taking place at a meeting point of these systems with other bodies, including metals. Can be classified in electrochemistry everything that relates to the liaison between the electrical and chemical phenomena.

f) The biochemistry, who studies protein structure and protein molecules, the functions of enzymes, problems and protein synthesis. in the body, the relationship of dependency between the chemical structure and. biological functions (activity) of proteins. La. biochemistry studies of key processes and complex against 1 'immunity and properties of proteins immunisantes

g). radiochemistry, which is closely linked to the problems of radio-activity and radioactive isotopes, use of atomic energy.

h) The physical chemical, which is interested in applying the results of modern physics, the basic problems of chemistry, and specifically the issues of the structure of atoms and molecules and. studying the mechanism intimate chemical reactions.

i) The chemical kinetics, science chemical transformations. who die speeds and directions of the chemical reaction. The development of a general theory of the process chain and the discovery of possibilities to control chemical reactions chain depend on the development of this branch of chemistry.

The progress made by the physical sciences and chemical sciences have an influence on the biological sciences â It is from physics and chemistry that biologists dealing with energy efficiency and â studying the complex processes that are place in the living organism, and vice versa. â chemistry seeks to use biological principles to solve the tasks of chemical synthesis.

 

III The biological sciences

Recent discoveries of physics, chemistry and mathematical methods have led to a revolution in the biological sciences. Molecular biology has revolutionized the science of World kids living in proportions that quantum theory has revolutionized the nuclear physics that there are forty years.

The intense study of the biological functions of living beings. from the analysis of the structure and molecular interactions gave biochemistry leadership, leading to a relatively new science - molecular biology. In kid time, the establishment of the principle of catalytic functioning of living matter was a fundamental for the development of biological science.

Take the seeds in the biological sciences
The ferments are in many ways incomparably superior to artificial catalysts. Before their power by any action, thousands of chemical reactions take place in living organisms. Using ferments, in the absence of high temperatures and pressures, millions and billions of times faster in the presence of the best chemical catalysts.

The ferments have yet another benefit - the most important. They differ catalysts artificial rationality surprising for their actions, strictly oriented and maximum efficiency. Each closing act in an optimum manner, without finding technological solutions optimal 'in transforming not only one compound or a group of very close. and transforming them in a direction strictly determined.)

The discovery and description of a growing number of biochemical reactions â put the agenda the task of trying to establish the fundamental principles that govern the nature and interdependence of these reactions. Without that. it was impossible to develop a systematic process alive, countless biochemical terms.


The solution of these problems was first linked two basic discoveries made in the thirties and forties and have been essential elements of the revolution in the biological sciences, particularly on the biochemical level. The first is the discovery of "conservation." Energy of biochemical reactions in the form of chemical bonds in a particular matter which received the name of adenosine triphosphate. The second is the discovery of the principle of combination reactions in biological systems, ie that the surplus energy formed in response to a course can be transmitted to another reaction that would not be d 'Itself possible.

These two basic discoveries immediately bring the logic in research on the biochemical organization of the activity of cells to distinguish combinations reactions energy. eligible and ineligible. Thus began the assembly of biochemical elements in separate groups or mechanisms intact, and when the researchers took fiai to operate on a certain segment, they found they managed to swallow train, from components, or as Such physiological process whose biochemists had initiated the development thirty years ago. ' " [7]

The subsequent progress of science, a deeper penetration of the secrets of life discovered was able to process more complex than photosynthesis and respiration, biochemistry did not yet understand. It was primarily the process of growth and development as well as the phenomena of heredity and its transmission.

Neither the methods and experiences of physiology, nor those of biochemistry were unable to highlight the properties of living matter which constitute the substance of these phenomena. Only with the advent of electron microscopy that we put into the unknown world of the infinitesimally small particles of the living cell. Thus the practical results of the revolution. Intervened in physics were a powerful catalyst for the revolution in biology. If the power separator ordinary microscope can achieve a magnification of two to three thousand times, the electron microscope can magnify objects of study of hundreds of thousand times and even more than a million times. The amount converts to quality basic opportunities have opened to the study of microscopic organizations, intimate process taking place in the living cell.

In entering ever more deeply into the secrets of the process alive,. biological science learns about the mechanism for the use of genetic information. Thus, biology was brought to explore the giant molecules of organic polymers: nucleic acids, proteins and some carbohydrates, ie training, which play a decisive role in the performance of vital functions essential. The study of these molecules required methods and processes hoc analysis and constituted one of the key orientations of a science booming molecular biology, we talk a little further.

The results of the biological chemistry were and still are today an grazing tool knowledge of life processes. But the language of chemistry did not allow itself to penetrate the mysteries of life. The biophysical came to the rescue. The search continued for solving the problem of living has enormous methodological and practical importance for the development and improvement of material production,

Academician G. Frank wrote "What we call the living can not be translated into language purely chemical. In addition to the list of reactions involved in the process of exchanging chemical substances, in addition to the catalytic reactions and chemical kinetics of these processes, there must be some organization in space (structure) of all rnacromoléculaires, which is beyond the framework representations purely chemical. " [8]

This organization, writes G. Frank is not only the location of chemical processes; acting itself is changing, determines their conduct and organise. That is why, alongside the chemistry and molecular approaches, we need what might be called conventional language of 'approaches surmoléculaires "These approachessurmoléculaires can not already under the sole jurisdiction of chemistry and biochemistry. We are witnessing here are qualitatively different processes and chemicals added to the forces of interaction phenomena characteristics of the system surmoléculaire complex. The study of these phenomena is usually biophysics or physical chemical biology " [9]

The biological sciences naturally attach particular importance nature of the activities of living organisms and their smallest components in the cell and components of the cell itself. Science has entered into the inframicroscopique structure of the cell, which allowed him to make the most unexpected discoveries, forcing a radical revision of current ideas on the principles biochemical, biophysical and physico-chemical properties of cellular processes.

"How is born. a new science, a new specialty? "asks P. Thuiflier thy has not answered both general and satisfactory this question, although various assumptions have been made. " [10]
This interpretation seems skeptical, because the development of a new discipline and the birth of a new science does not depend on the identity or the intellectual originality of ideas. Rather, it depends on the character of the nature of the subject of science itself method of exposure in the wider it is the means to achieve an objective, an activity according to a certain orderly fashion. It is by methodological role that tears the veil to the extraordinary complex phenomena of nature, society and the human conscience and directs the science to the release of natural links, objectives, forcing the researcher to stay on Field facts rigorously established. For example, lob jet of molecular biology is to study the events essential activity vital to their elementary levels in the cell and its components, the nucleus and the cytoplasm, in the tiny intra-cellular structures, systems the simplest located on the border of living and not living like virus and bacteriophages, and finally, in systems of biological macromolecular polymers and proteins nuclides acids that carry out its essential functions in training live ...

There is a particularly intensive development of molecular biology research related to problems of proliferation, heredity, structure and. properties of macromolecular compounds, their biosynthesis and laws of their reproduction in the process of growth, division and cell development.

In other words, bios macromolecular polymers and nucleic acids are essential objects of research in molecular biology.

Over the past thirty years, biology has undergone a profound transformation by the convergence of disciplines for a long time remained independent of both the problems they saw as the equipment and methodology they used. Thus, the cellular physiology, genetics, biochemistry, virology, microbiology have melted into a common discipline, which is now known as the molecular biology. It aims to interpret the phenomena that take place within living organisms in office structures and functional interrelationships that occur between macromolecular constituents of the cell. [11]
In its first stage, molecular biology has sought to analyze the material the simplest cell, namely the bacterial cell, that some discoveries were made accessible. such a study. In recent years, the elucidation of the main structure of biological macromolecules, proteins and nucleic acids, the interpretation of their functions in terms of structure, recognition of their biosynthetic pathways and their regulations have renewed our knowledge of heredity and cellular mechanisms. "

This feels the development and differentiation, more interconnection of science that results, models and methods of some sciences are becoming more widely used in other (for example the use of physical and chemical dodèles in biology and medicine), and this shows the problem of interdisciplinary research. Another important feature of the current stage of development of science is to increase the role of constructive elements in scientific knowledge. "On the one hand. In entire body, others share in somatic cell cultures taken from the bodies complex.[12] "Because the discovery of the nature and structure of nuclei acids demonstrates the rationality of the exceptional nature and organization of his creatures, in fact, nucleic acids are composed wholly of four elements: the four nucleotide that does differ from one another by their nitrogen content - adenine, guanine, cytosine, themine. Thus, the tremendous diversity of. life on. Terre A. always a basic biochemical perfectly unique and universal. Moreover, the principle of complementarity, which explains the old secret of heredity, is one of the essential bases. molecular biology with which it was established that in a DNA molecule, the amount of guanine is always equal to. the amount of cytosine, adenine quantity is a égaie. the amount of themine. During the vital activity of the body, the DNA molecules involved in trade undergo many cellular damage under the influence of internal and external factors. Thus, the new directions of development of molecular biology and its revolutionary continuous progress based on solid methodology.

"It is the combination of organic synthesis and very fruitful, two methodological approaches. the study of nature and properties of the simplest components of a complex, and the study of the structure, organization, the properties of complex body as a whole, forces and processes that constitute the system as. than anything else.

The key question is how simple it gives birth to the complex, what are the forces and laws that are operating here, how to structure new properties of the complex system.

It is a focus of scientific research that part of the molecular levels the most primitive and the most basic driving è, levels of organization of increasing complexity,. systems with new properties and functions.[13] "

The essential feature of this passage from simple to complex is an integrated process, we propose the term of fundamentalism to define the orientation of cognitive science.

If one analyses the development of natural sciences, technical and social, one finds much in common in their methodology and practice.

Thus, this methodology is it absolutely necessary as regards the creation of automated systems that the development of the vast majority of complex programs, as it is to solve the problems of the relationship between the party and everything between simple and compound. The need for such a methodological approach is more apparent than ever today as regards the solving of economic and socio-economic and development programmes in which we have always dealing with large complex systems to several components .

D'oc current problem 1 "fundamentalism" for all the natural sciences, technical and social. The mechanism of development of science in their process of unification of the different branches of science plays an important role in guiding scientific thought and technology of our century. 11 opens two possibilities for developing and refining the material productive forces, through which we can see the development of the revolution in the natural sciences, technical, social interaction and their dialectic in two aspects:

First, humanity will affect so focused on the processes of organic life and from it. Raising a colossal effectiveness of social production, and also increase the possibilities of the man himself - the first productive force of society - and the perfect considerably.

Secondly, the company will continuously introduce into production the results of technological and organizational organic life> and. From then allow a new scientific and technological revolution which, it has every reason to think, leave it far behind the possibilities opened up by the current scientific and technological revolution.

This revolution in the biological sciences wakes up the "technical", "" technology "and the organization of operating systems which exceed in complexity all the systems that man has been able to create and productivity have never seen in practice the global industry at the same time that capacity, an infinite number of dimensions, economic performance and reliability unimaginable.

The active phase of the revolution in the biological sciences began, it seems, most recently as physics and chemistry, and its practical results may not be as clear and important that the results achieved by physicists and chemists, but it is already visible today that the possibilities, both cognitive and practical, opened by the revolution in science are of a magnitude that they can serve as a springboard â. a new revolution in science and information technology, which means the development of physical sciences, chemical, biological as the basis for development and differentiation branches scientific computing,



                 
THE CONFERENCE OF THE ACADEMY OF SCIENCES

On 13 May 2008 next section of molecular and cellular biology, genomics of the Academy of Sciences will organize a conference on epigenetics and cellular memory. This is a new discipline of molecular and cellular biology, genomics. The question that arises What is epigenetics?

It is often at Conrad Waddington (1905-1975) attributed the invention of the term "epigenetic" in 1942, to appoint "the branch of biology that studies the cause-effect relationships between genes and their products , Showing the phenotype. " The first mention of epigenetics in literature has emerged in the mid-nineteenth century, but it can be traced back the origin of the concept to Aristotle (384-322 BC. AD). He believed in a epigenesis: ie developing an organic form derived from individual informs. This view was contested the main argument against a form of development from tiny body already trained. Even today, the question of how far we are preprogrammed or shaped by the environment continues to arouse controversy. The field of epigenetics has emerged to fill the gap between innate and acquired. In the twenty-first century, the most common definition of epigenetics is "the study of heritable changes in gene function, taking place without alteration of the DNA sequence." But see what scientists who work in this burgeoning field have to say on the subject… "Epigenetics has always been all these weird and wonderful things that genetics is not explain. " [14]

"DNA is like a tape recorder carrier of information, but that is useless without a tape recorder[15]. Epigenetics somehow plays the role of tape. According Jörn Walter[16] "I take a photo of a computer and I comparerais DNA to the hard disk and the software epigenome. You can access certain information on the hard drive through the programs installed on the computer. But there are some areas that are protected by passwords and others who are not. I would say that we try to understand why there are passwords for certain areas while others are free to access. "For Gunter Reuter[17]" There are about two metres of DNA into a nucleus that is only a few micrometers. We try to understand the mechanisms that allow access to DNA, despite the tiny size of the kernel. "

In essence, genetic and epigenetic switches determine whether genes are active or not. These are proteins encoded by the DNA sequence, called transcription factors, which play the role of genetic switches. The epigenetic switches, they consist of chemical modifications of DNA and histone proteins associated with him, as well as changes in the structure of chromatin, the complex. proteins and DNA that constitutes the chromosomes. Moshe studies the role of these switches in biological processes as diverse as type II diabetes, kidney disease polycystique, development of organs such as heart and liver, and the transformation of cells into cancerous cells. Increasingly the revolution in genetic engineering has invaded space science. "Information management in the kernel requires that a portion of genetic information is extremely compacted in the genome. Moreover, another part of the genetic information must be turned on and walk continuously, as the genes so-called "household" for example. So epigenetics looks a bit like the way it organizes his papers at home: we keep handy those that are used regularly, but range old report cards in boxes that are being Grenier.[18] "You can probably compare the distinction between genetics and epigenetics the difference between writing a book and reading. Once the book is written, the text (genes or information stored in the form of DNA) will be the same in all copies distributed to the public. However, every reader of a book will have a slightly different interpretation of history, which will bring him to emotions and personal projections over the chapters. In a very similar, epigenetics allow several readings of a fixed matrix (the book or the genetic code), giving rise to various interpretations, depending on the conditions under which we interrogate this matrix. "

Thomas Jenuwein think that more than 50 years have passed since the first publication by
Watson and Crick on the three-dimensional structure of the DNA double helix. Now that the Darwinian theory of evolution has found its way into people's minds, the discovery that DNA code for hereditary characteristics is widely accepted. When Crick left us the extent of media coverage has shown how this concept was recognized well beyond the scientific community. However, we start to realize that the theories of evolution focused on genes have a limited scope. The genetic master plan, just like a complex musical score, remains lifeless without an orchestra of cells (musicians) and their épigénotypes (instruments) to interpret.

             Science lifts the veil today on how to play our partition genetic interpretation is apparently radically different from one generation to another without the DNA sequence has undergone change. The field of epigenetics seeks to determine how the mechanisms regulating the maturation of molecular genes affect the function genomics. Among the epigenetic factors, there are both the spatial organization, such coiling of DNA around proteins called histones (chromatin), biochemical and labelling.

                 There are hundreds of different types of cells in the body. Although each has the same starting point, the characteristics of a neuron are quite different from those of a liver cell. For some 30 000 genes that account the human genome, the importance of silence, as in any orchestral interpretation, should not be underestimated. As the cells grow, their destiny is governed by the selective use and putting in silence genes. This process depends on epigenetic factors. The profiles of DNA methylation plays a role in all sorts of phenomena which genes are turned on and off, whether the stain on a petal purple petunia or development of malignancies.

               The inability to reduce to silence some genes can generate a dangerous cacophony. An insufficient methylation of DNA can alter the organization of chromatin, which then influence the genes to be put in silence after cell division. An excessive methylation can destroy the work of tumor suppressor genes and DNA repair, which have a protective role. The épimutations of this kind have been observed in all kinds of cancers. These discoveries epigenetic pave the way for the exploration of new therapeutic possibilities.

                Epigenetics also provides the genetic material means to respond to changing environmental conditions. Although plants have no nervous system nor brain, their cells have the ability to memorize the seasonal changes. In some species biennial, this ability is linked to their ability to bloom in spring, when they detect ambient temperatures more lenient. Research on certain types of watercress have shown that exposure to cold during the winter causes structural changes in chromatin, which reduce the genes of flowering in silence. These genes are reactivated in the spring when the days longer and hotter become suitable for breeding.

                   The environment can also cause changes that will affect future generations. Laboratory studies on mice consanguineous have recently demonstrated that a change of diet may influence their offspring. They may have a brown coat, yellow or spotted depending on how the agouti gene is methylated during embryonic development. When females were in gestation with a diet rich in methyl supplements such as folic acid and vitamin B12, especially their offspring has developed a brown coat. Most small set by the World mice witnesses (who had not received supplements) had a yellow coat.

Like the conductor inspires the dynamics of the execution of a symphony, epigenetic factors govern the interpretation of DNA within each cell. Understanding these factors could revolutionize evolutionary biology and development and influence on practices ranging from medicine to agriculture. In response to Watson, "the genetic alphabet would rather God's word and its translation would hand."

Moshe YANIV, the Academy of Sciences, Institute Pasteur, Paris has interpreted the question Epigenetics and Development[19] said al clearly "Our text genetic DNA, is the same in all cells of the body. Yet the information given by the text was not read in the same way in our cells, and this contributes to the formation of various tissues and organs that make up our individual. This  the cell line is permitted by changes in proteins that coat our DNA, histones, and by methylation of DNA or RNA molecules. These changes lachromatine are transmitted during the duplication of our chromosomes, allowing them to keep in mind during cell division. Abnormalities of these epigenetic changes can lead to various diseases including cancer. This panel discussion will illustrate the recent progress in this new discipline which represents an important shift in our understanding of heredity and the biologica[20]l variety. " As for Adrian Bird[21] he studied Adrian studying the methylation of DNA, ie chemical changes thereof encoding information that is added to that of the DNA sequence. The DNA methylation plays a major role in putting in silence genes and Adrian found proteins that bind to methylated DNA sequences and participate in this mechanism. Mice that lack one of these proteins, MeCP2, develop a disease similar to human neurological disease[22] called Rett syndrome. In seeking to identify the genes that are activated by inappropriately in mice deficient in MeCP2, Adrian hopes to advance therapeutic strategies for this disease. "In his presentation to the Conference of the Academy of Sciences Andrien Bird believes that" DNA vertebrates covalent DNA is modified by methylation of cytosine in the dinucleotide sequence 5'CG3 "and that thought is regarded as a form of cellular memory. One way to understand the "epigenetic" brand, is to study proteins that "read" methyl-CG signals in the genome. MeCP2 is of particular interest that mutations affecting its gene causes Rett syndrome, the most common inherited form of mental retardation affecting women. the molecular level, to speak briefly on the structure and dynamics of MeCP2   binding to methylated DNA. At a higher level of complexity, experiences that test the reversibility of Rett syndrome-like symptoms MeCP2 null-mouse will be described.    Combined and molecular neurobiological information supports the idea that the functions of MeCP2 maintain programs gene expression in neurons mature. " [23]


  Robert Feil would like to know how genes printed, which intended to be activated or deactivated is predetermined by their parental origin, influence the development of the embryo into a fully formed body and that of extra-embryonic tissue such as the placenta. A fairly large number of genes have been discovered printed but you do not understand very well how cells know which genes were inherited from the mother or the father. The DNA methylation, a chemical modification of DNA, contributes to this process of recognition in the embryo. Robert seeks to ascertain how changes. The chemical histone proteins could play a role in the formation of the footprint.[24] According to Robert Feil "Among placental mammals, the genome inherited from the mother and one inherited from the father are not functionally equal. They are, during pregnancy, both required for a healthy development of the embryo. The functional necessity of both parental genomes estdue a different marking between the sperm and egg. These epigenetic marks on the parental chromosomes persist during development and allow the allelic expression of certain genes from the copy is maternal or paternal. About a hundred genes are controlled by this phenomenon epigénétique called "footprint genomics." Most of these genes under the imprint plays a fundamental role in fetal development and growth, while others affect the behaviour after the birth. Thus, it is not surprising that disturbances pathological del'empreinte genomics lead to disease and behavioural development in humans. Some disturbances in the footprint are also involved in cancer. After an introduction on the biological significance of the impression genomics, I will present some examples of recent research on the molecular mechanisms of the impression genomics. "In other words, the footprint genomics and its role in developments in placental mammals, the maternal and paternal inherited genomes are functionally not the same thing. Both are required for embryonic development and well-being during the gestation period. Techniques need both parental genomes is a consequence of differential "Épigénétiques marking" in the egg by sperm. These differential marks on the chromosomes (fingerprints) persist in the developing embryo, and after birth, and transmit the presence or the expression of genes from either their mother or father copy. About a hundred genes are
controlled by this phenomenon called epigenetics "footprint genomics."  Most printed genes known to play a key role in fetal development  and growth, others influence behavior after the birth. Not surprisingly, therefore, pathological disturbance footprint genomics gives rise to
related to growth and behaviour of disease in humans, and is associated  with cancer as well. After you submit the biological significance of  footprint genomics, I will present some examples of recent research on  the molecular mechanisms underlying.

 


As for Giacomo CAVALLI[25], it uses a fly vinegar as a model organism to study how proteins groups Polycomb Trithorax and regulate development. For an organization to develop properly, the subset of genes has to be activated at the right time and in good cells. The group Polycomb proteins disable certain genes, whereas proteins Trithorax group to activate other. Giacomo has discovered that these are specific DNA elements that determine whether or not certain key genes of development are activated or not by this mechanism when new cells are formed. With the help of colored markers and sophisticated microscopy techniques, Giacomo examine how these elements can ensure that remote areas on chromosomes can come closer to each other.

 

The truth is that "epigenetics respect to the transmission of hereditary characteristics of each cell type in the same body. Many biological processes essential for the development and adult life depend phenomena "epigenetic", ie that different cells and tissues acquire "identities" different, even if the DNA of each cell is identical. These identities are kept permanently throughout the life of cells and are passed on to daughter cells so hereditary. We now know that this is the chromatin structure which is the identity of this cell, which transmits the daughter cells within the same lineage. But the structure of different chromosomal regions is regulated by factors called Polycomb "and" trithorax. " The Polycomb proteins lead to the formation of structures condensed and inactive, while proteins trithorax open the chromatin and allow the DNA to express its genetic information to obtain cellular RNAs and proteins. We showed that the Polycomb proteins and trithorax can transmit a hereditary memory states activated and repressed by their target genes. We seek to understand the mechanisms underlying this memory and their role during normal development and in the context of the emergence of cancers. "In other words in the field of Epigenetics regard to the transmission of hereditary traits that distinguish each type of cell in an organism. Many biological processes depend on epigenetic components that are capable of driving different cells in different cells States fate despite the fact that they share the same DNA sequence. These cellular identities can be transmitted by cell division, this implies cellulairemémoire the regulation of DNA in chromatin emballage.Les proteins Polycomb group (PCG) are able to transmit the cellular memory of silence States of gene expression, while trithorax group (trxG) proteins, silent struggle with a function of activation that allows them  target genes to express themselves in the types of cells. Our research  showed that these two groups of proteins can transmit the memory gene  States of expression throughout development and even through meiosis in
descendants. We are therefore trying to decipher the molecular mechanisms that  are responsible for the maintenance of this memory under normal conditions  development, and understand how the disturbance of memory cell  generates diseases such as cancer. " [26]

Minoo Rassoulzadegan[27] and his staff of Inserm Unit 636 "Genetics of normal development and pathological" *, describe a mode of inheritance which does not comply with the laws of Mendel. It involves the transfer RNA molecules associated with the genome - in particular the recently discovered class of microARNs-, in the head of sperm. This very special heredity was identified in the case of an epigenetic modification called hereditary paramutation, in mice. The paramutation used in this work affects a gene essential for development whose modification can be followed by a change of colour coat. These results may be closer to work very recent showing the presence of RNA molecules in the human sperm, and bring about their possible functions of the new assumptions.

The change is an epigenetic modulation of the expression of genes or groups of genes which, unlike the mutation does not change in structure (nucleotide sequence) of DNA. It is nevertheless passed on a stable during cell division. One of the most studied examples of this kind of variation is the inactivation of one of the X chromosomes in female mammals. This type of change is today considered important in various diseases, including cancer.
In plants, a class of epigenetic change is considered as "paramutation". It is characterized by its property to be not only stable during the development of a body (somatic level) but to be transmitted to offspring during cross over several generations (germinal level) with distributions different from those predicted by mendelian. Comments earlier laboratory and an American group suggested they might exist in animals. Heredity paramuté character does not follow the rules mendéliennes, the majority of offspring showing the change. Although transmission by the mother or the father is also effective, Minoo Rassoulzadegan and his colleagues decided to study the formation of male sexual cells, easier access. There is a state paramuté an abnormal accumulation in the precursors of germ cells (spermatids) degradation products of the messenger RNA Kit and two microARNs specific gene. Recently discovered, microARNs constitute a class of complex molecules very small (20-22 nucleotides), each with a specific gene or group of genes. An important role was very recently recognized in controlling the expression of genes at different levels: degradation of messenger RNAs, inhibition of translation and modified structures of the chromatin.

            This accumulation unusual RNA into precursors germinal led researchers of Inserm to examine sperm from males paramutés. Through various techniques, they observed a significant amount of RNA molecules, while the sperm of normal mice did contain very little.

            To show that the transmission of epigenetic change was due to the transfer of these RNAs during fertilization, RNA molecules (including two microARNs specific Kit) were introduced by microinjection of a fertilized egg cells from a normal couple (1 stage embryos cell). After relocation in surrogate mothers, a fraction (50 to 60%) of embryos treated produce animals carrying the modification and themselves capable of transmitting it to their offspring. The other microARNs used as witnesses not cause any change of colour coat. ). It is an alteration of the character determined by a gene when it was transmitted by a parent heterozygous who he was facing a form (allele) moved (there was talk of "conversation interchromosomique"). On the one hand, contrary to the law of Mendel, which states that the alleles were left unchanged during segregation during the crossing, is not respected. On the other hand, the amendment is stable and will be transmitted to offspring, although the sequence of nucleotides in the gene "paramuté", so the genetic text itself is not modified. The first case of paramutation observed in mice was an amendment to the wild form of a gene (Kit) in the offspring of a heterozygous with a mutated form. The mouse
heterozygous (Kit-/Kit +) is characterized by white coat (tail and feet), a class of characters visible, and therefore easily detectable that the likes geneticist since Mendel. This phenotype identical to that of mutant is transmitted in the absence of the allele inducer, so by animals carrying two alleles structurally intact, and that over several generations. The signal inducing altered state was found to be the transfer RNA molecules in the embryo at the moment of fertilization. We observed a significant burden RNA in the sperm of males "paramutés." Experiments reconstruction based on the injection into the egg fertilized mouse normal RNA of these animals, as well as synthetic RNAs and microARNs specific locus, have established their role inducer. We have recently extended this mode of hereditary transmission over several generations of pathological situations, including a pathology in mice reproducing a serious cardiac malformation (Wagner et al., 2008). It can offer a model for diseases so-called "family," observed repeatedly between parents and children or between brothers and sisters, while in many cases, it could not identify a genetic alteration of the text (changing) . Beyond the inheritance of a genetic text, we now consider heredity its modes of reading. " [28]

  Marcel MECHALI, [29]considers that the harmonious development of an embryo requires a delicate balance between proliferation and differentiation of cells. A similar regulatory control the renewal of our cells in our adult life. Each division is non-seuleument our genome that we must duplicate, but his organization for differentiation incurred. Marcel interested in the role of replication origins in that balance. The research conducted in his laboratory has shown that the origins of replication were regulated during development, in conjunction with a remodeling of chromosomal domains. Marcel also identifies new factors replication, and his team discovered the role of CDT1 and MCM8. How do these factors could be deregulated in cancer is a question asked by his laboratory.

          In his presentation entitled The inactivation of the X chromosome: how extinguish a chromosome with the NRA Claire ROUGEULLE,[30] Pasteur Institute, Paris says that "The inactivation of the X chromosome is a fundamental process that ensures, among mammals, a strength equivalent gene among individuals male (with 1 X chromosome) and females (with 2 X). The inactivation takes place very early in the early embryonic development of females and is characterized, in fine, by the extinction of transcription in virtually all of some two thousand genes carried by the chromosome affected. The inactivation is often seen as a paradigm of epigenetic regulation insofar as it implies that two homologous chromosomes (the two X chromosomes) behave differently within a nucleus, one active and the other being inactivated . In a surprising, it is known that the main actor of this process is a non-coding RNA, the expression from one of the two X chromosomes leads to inactivation of the latter. How RNA can it extinguish an entire chromosome, and how this RNA is itself controlled are two crucial issues to be discussed. " [31]

 

CONCLUSIONS

Our research has asked these questions twenty years ago have been the subject of the Conference of the Academy of Sciences but I can highlight the three basic functions of the Academy of Sciences.

 

Twenty years ago before the jury academic and scientific I submitted the following statement.

On what grounds can we ponder over the nature of science classification and what links can we establish between the classification and computer science? Where do the ideas on computer philosophical foundations come from as a base for the foundation of the Academy of Sciences and of the National Center for Scientific and Technical Research of Kurdistan? Do these ideas come from an issue on the historical development of the science classification or do they come from another methodological or epistemological nature? In other words, does the history of the philosophy of science need such a theoretical and philosophical explanation of the issue on the scientific reorganization of knowledge and its foundations? First, how can the opposition between both notions constitute a unity, especially with notions that do not stand in the same context? On one hand science classification is an old issue that goes back to Aristotle and which was a more philosophical issue than a scientific one in the Middle Ages, so that is an encyclopedic issue. On the other hand computer science gets a very varied meaning which has directly no links with the notions of science classification which are not on the same level. .

First, a prevailing tendency is found among French and European computer scientists and there is an approach to the definition of "a computer science "or" computer sciences "or" computer scientific branches" which is linked to the definition of technology. The computer scientists of today are looking for the nature of only one science " (the computer science) and they reject the division of the intellect and the differentiation of sciences, their detachment from computer technology, without considering the scientific and technical progress. On one hand this belief of one science coincides with the positivist philosophy which rejects its role of «Science of sciences ". On the other hand the tendency stems from the thought of Marx and developed by Engels, defends the unification of the human science with the natural science in order to  create one science only....

Under those conditions, "is there one or several computer sciences"  J.D Warnier asked. Then he added «as far as the axioms and the basic principles are concerned, there is not an only science ". What are the differences between «the axioms and the basic principles «of computer science and those of philosophy? If there are no differences, how can we study " as many computer branches as we discover branches of the human activity which need word processing that is to say data processing, not only as far as applied sciences are concerned but also in the technological structure of the scientific and computer branches ? How can we tell the fundamental computer science in general from management computers, scientific computers, telecomputers, telematics or the computers of satellites which have different missions? From the computer science analysis, can we introduce  the field the classification of techniques that is not made any longer according to the products but to the processes in order to establish links with the science classification ? In other words the classification was interpreted by the philosophers of the 19th century like the connection of sciences and it didn't lead to the reduction of philosophy to an only science as Marx pointed out: «how will natural science later embrace human sciences as well as human sciences include natural science, and will there be an only science?" What will be the function of computer science in the fulfillment of the scientific combination? Will there be an "only computer science» or several computer sciences within the process of the realization of the combination? But we may ponder over the origin of those computer scientists looking for the nature of an "only science" (computer science) and who reject the diversification and the differentiation of the computer scientific branches. Where do they go to? Which tendency of science do they go to? To an «only science» as Marx suggests or to the «only science» developed by the neopositivists of the logical positivism? If those scientists get close to the Marxist conception how will the natural science embrace the human science? But if they get closer to the neopositivist doctrine or to the logical positivism what will their function in the sciences centre be if the human science includes the natural science? Which criteria allow us to distinguish the logical analysis of the science which claims to organize the scientific knowledge within the scope of an "only science"? What is the meaning of the value of an "only science" for the science philosophy of our century? How can we look for the philosophical foundations of computer science if there are some differences between the "axioms and the basic principles" of computer science and philosophy?

First question: What is data processing? Is it a science, a technology or various techniques? What are its aims? If it is considered like a science, is there one or several computer sciences? What would its function in the science classification be? If it is considered like a technology and if we define technology like the science of the scientific and the technical rules of the production process, then, what is its function as a physical, technical and mathematical science, in the science classification? What are the differences between technology in general and computer technology? If it is considered as a technical whole, what are its connections with science and the human being? What links can we establish between the science classification and the various application fields of computer science? What is the computer science methodology? What are the features of a pattern of the science classification and computer science?

 

Second  question: What is classification? What does the science classification mean nowadays? What are the aims of science? What about their classification) How can they be in harmony with the numerous human experiences.  What is the specific characteristic of the issue for the human science philosophy ?

Third question: is there a computer science classification? What are the bases of the various scientific branches of computer science? What links can we establish between science classification and the scientific and technical revolution?

Fourth question: What are the prospects of the scientific development for a new humanistic civilization and what conclusions can we draw?

 

METHODOLOGY

For our philosophical processes, we have used the dialectical method. First, we have pondered over computer science by developing the logical and mathematical basis and the linguistic basis of computer science. Then, we have taken interest in the historical issue of science classification and we have intended to show the connection between science from the natural rules, its outcomes and the objective links between the function of the various sciences within their development and their own changes. Finally, we have studied the physical chemical and biological science as the basis of the differentiation of the scientific branches of computer science. We have analyzed the classic and modern computer system, the dialectical process of human knowledge in philosophy and computer science (the artificial intelligence and the foundations of the scientific knowledge) to establish the links between philosophy and the scientific revolutions and the aspects of a new conception of humanism in the scope of a new science classification.

What is data processing is it a science a technology or does it embrace all techniques and tools?

According to the Academy of Science, data processing is "the science of the rational processing, especially with automatic information machines considered as the basis of human knowledge in the technical and social fields.  "This definition provided by the Academy of Science is our starting point but we have broadened it.

First, computer science is a physical, technical and mathematical science linked to the second part of the natural science classification. That implies:

1. Computer science is both a rational processing science and a systematic, logical and mathematical science. It needs the analysis of the logical and mathematical basis of computer science (the binary logic and the Boolean logic)

2. Computer science is the science of the automatic data processing with machines and computers.

So, it is both a physical computer science and a technological computer science that implicates the other scientific branches like telematics or telecomputers which is linked to the study and the creation of the components and the electrical and mechanical subset that are part of the creation of computers. It requires the analysis of the physical and technological foundations of computer science.

3. As a science of the rational and automatic analysis of information considered as the basis of human knowledge and communication computer science it leads to the creation of several scientific disciplines : the epistemological computer science, the knowledge engineering, the artificial intelligence, Experts systems, the survey of the shape, the synthesis of the word, the interaction between men and machines, the development of the communication engineering in the field of telecomputers and the computer technology of satellites.

4. As an applied science of production, computer s c i e n c e it has some results as far as the production diversification and the scientific work division are concerned.

So, we have seen the logical and mathematical foundations of computer science. The Boolean logic is used in the systematization of the scientific knowledge in computers as a tool to argue. It is said that this mathematical logic is also the result of the logical and mathematical thought of Leibniz and that it is the basis of the philosophical and linguistic ideas developed in Ars Comniatoria (1666). Then we have divided the historical activity into four basic periods and we have studied the linguistic foundations of computer science "from Lavoisier's pictures which express the world into a new symbolical or expressive chemistry till the sophisticated classifications from which the living can enter a systematical reason" as Professor Dagognet wrote. The basic idea of his philosophy deals with the ORDER of reality and the linked possibility that the scientific knowledge cultivates. From this point of view we have analyzed the different languages: COBOL, FORTRAN, List Processing, ALGOL, BASIC, PROLOG, PASCAL. The growth of the languages suited to computers relatively corresponds to the needs of society. The scientific improvement based on the fundamental research in science widens the field of the labor force with the differentiation of the software technology.

So, we have briefly studied the structure of the computers called digital computers as opposed to analogical computers. They deal with digital information that is to say the continuous and discontinuous analogical and digital information which is the basis of computers classification. This technology gets a final logic in the material and social practical experience of the world. Indeed, "technology implies a reflection on the mode of connection. It is the place of change from the scientific rationality to the rationality of human science. So technology is the science of the control of information (especially scientific information) between men" Nevertheless there is historically a deep and converse connection in an explicit and systematic way between technology and science classification. The most remarkable of these classifications is Ampere's. So what is classification?

What is classification?

In French, the classification supposes a scientific attention and a theoretical order, I mean, it is built on a rational knowledge on the classified things and it allows one to understand them.

Classification is an example of logical process used in science or in practice. Classifications are made according to the basic characteristics of the things. Classification emphasizes the similarity and the differences between things. So, the classification is a cognitive activity whose objective is to divide up the beings according to their similarity. It is a representation of the whole systematic knowledge, especially in science, of a system of divisions and subdivisions. Sometimes, when it is only a matter of organizing things in a system, we base our divisions conveniently even if things have no links between one another.

Classification is the share-out of things in several coordinated and subordinated sets. It is the way to organize concepts according to the connections we want to emphasize: connection from gender to species, connection from the whole to the part, genealogical and hierarchical connections and so on ...In the field we deal with three main kinds of classification. First, there is statistics, that is to say the automatic classification that allows us to draw, thanks to algorithm, several partitions according to the individuals. Then there is the biological classification found by Linne. It is based on the obvious similarity between species that are placed in the same set. But this kind of classification is not very common. Finally there is the classification philosophically speaking.

So, we have considered in detail four main stages in the development of science and knowledge: the immediate intuition stage, the analysis stage, the synthesis stage based on the former analysis (the upset object of knowledge is mentally pieced together in its entity and in its former reality). At the stage the differentiation of knowledge has been doubly characterized: first, according to the material object, it is different from the former science; then, according to the lower form of the nearest movement thanks to which it is linked to the former science. The characteristics of a science and the differentiation of its knowledge get objective foundations on each new science. Such a connection can be made because the lower form of the movement enters the upper form just as the upper form just as the movement of a molecule enters the physýcal state of gas (thermodynamics. So, this dialectical unity of the material movement and of the

scientific knowledge on the real world, constitutes a real basis on which you can build a model of the dialectical classification of sciences and you can give each science an accurate definition that can indicate its place in the new sketch of science classification. For example, the nuclear science is a science you can deal with at the edge of its often fleeting experimental facts. This science makes sophisticated materials intervene. The problem posed to the physicians is the following: which model of the nucleus can we propose to explain the observations and the experimentation in keeping with the rules of atomic physics   If nuclear physics is a scientific branch of atomic physics, so, it has given rise to energy and has become differentiated from the nuclear chemistry and the other scientific branches of atomic physics. How can we explain the basis of the law of changing from quantity to quality from a science to another as far as the development of the basic contradiction is concerned? Will this contradiction lead up to a new approach of the classification?

Which model of science classification can we propose to the problematical unity of the scientific knowledge regarding science computer science in keeping with the nature? Can the atomic model of classification be based on the dialectical (material is both divisible and continuous and at the same time and neither of them) and on the dialectical atomic components, and can we analyze and express any historical experience of science in the unity of the scientific organization of knowledge? In other words, will this approach establish the common foundation of the whole fields of knowledge? Explain the classification of dialectical rules the dialectical contradiction indivisible and unity of the

From this viewpoint we have tackled the basic principles of science classification. There are subjective, objective and comparative principles of science classification. First we have seen the subjective principle in Bacon, Hobbes, d'Alembert, Diderot as well as the rational classification in Comte according to the principle of coordination, the natural classification of science in Andre Marie Ampere. Then we have analyzed science classification according to the objective principle in Descartes, Gassendi:  the artificial classification in Augustin and Cournot :  the characteristics of the development of science classification in Germany thanks to Kant, Scheling, Hegel and the logic of the scientific connection in Marx. Finally we have analysed the dialectical classification based on the principle of subordination in F.Engels.

A first thought is based on the positivist thinking of A.Comte that allocates to the "authentic" philosophy a basic function. The positivist philosophy itself is a special science. The connection between philosophy and science is typified in this way: "science has its own philosophy". This connection is due to a definite interpretation of the role of science in culture. Neopositivism as a modern form of positivism deprives philosophy of its object without considering anything but the consciousness of the reality and the everyday or scientific thought. According to the positivist thinking philosophy is conceivable only because it is devoted to the analysis of language by which the mind can express itself. The philosophical analysis does not extend to the objective reality; it is limited to the immediate experience of language. According to the representatives of the logical empirism the phrase "philosophy of science" can apply to the research on philosophical thoughts on science and to the research on the probabilities of science. According to the logical positivism a real scientific philosophy is only conceivable as logical analysis of the scientific language. On one hand this analysis must suppress "metaphysics" (that is to say the traditional philosophy) and on the other hand it must analyze the logical structure of the scientific knowledge to make known the empirically verifiable content of the scientific arguments and concepts. The objective of this analysis is to reorganize the scientific knowledge in a "unique science" that erases the differences between physical, biological and psychological sciences and so on...

We must notice that the phrase "philosophy of science" is often used to name the ideas, the criteria and the principles used in the scientific processes. It is called "presupposition".

The study of the various scientific presuppositions is the subject of what we call "research on the foundations". This research used scientific methods such as axiomatization, the construction of models and so on... According to some authors (especially those who belong to the strict tradition of neopositivism) the only problems that can be posed about science are about the foundation. According to them the philosophy of science is a synonymous with the research on foundations. Only the adding knowledge is able to embrace the whole intelligible knowledge.

The second thought is based on Hegel's idea of foundation as a category of the system of the dialectical logic.

In Science of Logic Hegel analyzed the rules and the basic categories of the dialectical logic and the theory of knowledge. He developed the first system of the dialectical logic. The only law for Hegel is the law that unifies the law of gravity and the law of the celestial movement. The standardization of all the laws in the universal attraction is set down in itself. The universal attraction only reads that everything is different from everything; understanding thinks it has found a universal law which is able to tell the reality in its universality. By the way Hegel makes unification include in the conception of development even if he interprets in an idealistic way the main three fields of the object of the human knowledge: the natural world (nature), the historical world (society and its history), the spiritual world (human thought). According to Hegel, foundation is a reflection on essence that is foundation is the real mediation between essence and oneself. Foundation is first the absolute foundation as a basis in general; but more precisely it is determined as a form and a material and it is given contents. As a basic connection it becomes external to itself and it goes to the conditional mediation.

Foundation presupposes a condition, but condition presupposes a foundation too. Things in themselves go to the existence thanks to the mediation of the conditional connection. Indeed this "unification in an only conception of development in the natural world as well as in the historical and spiritual world" is the foundation of the Marxist thinking. It is composed of the dialectical materialism, the historical materialism, the political economy, the scientific doctrine of the society which has on one hand overturned the idealistic doctrine of Hegel and on the other hand it has developed a new conception of science classification.

So, according to Marx, philosophy can be fulfilled only by the abolition of the proletariat. With its triumph, the proletariat is nevertheless disappearing because of the birth of a society with no class and strictly human. For some people "this society is the real appropriation of the human essence by men and for men. It is the men return to themselves that is to say to social men -it is a total and conscious return which concerns all the wealth of the former development." For the other, it is "a utopia in an anthropological structure of imaginary." But according to Marx this society will put an end to the antagonism between men and nature, between men, between the individual and species, between existence and essence, between negation and assertion of oneself, between liberty and necessity thanks to the application of science to production in the process of the scientific and technological development as a material basis for the realization of the scientific unification. This new conception of science classification developed by Engels is a logical generalization and the reflection of the historical process. Four principles are developed: the principle of the reflection of the natural stages according to which science classification reflects the development of the movement within a peculiar local phenomenon consisting in the successive changes of the various kinds of energy. Then there is the principle of the development of the movement and its subset, according to which science classification is analyzed in a set : first as the reflection of the successive stages of the nature history and then as the natural science history. Then, as the history of the logically generalized and summarized natural science, that's to say as the continuous development of the peculiar sciences.

So we have studied the various forms of the mechanical, kinetic, potential and electrical energy from a macroscopic and a microscopic angle, and the caloric and biochemical energy and finally the nuclear energy.

With the study of Pauli's principles on the electrons, we have looked at the spectrum of the atoms of valency and we used the vector model for the atoms with dual valency electrons composed of four vectors of orbital momenta 11 and 12 and Spin momenta S 1 and S2. If in a low magnetic field, these vectors combine giving the vector of the total cinetic momentum of the atom J, so, we may find the basic structure of science classification from the elements of the regularity of the atomic spectra of the periodic classification.

This process gets universalized, science becomes a direct transforming and productive force and it exerts an influence on natural science as well as on social science. We replace the vector L (natural science) with the vector S (social science) and the quantum number J (unity of all the sciences). In order to note a better interaction between philosophical science and natural science and between social science and technical science, we will take into account the basic interactions between the elementary particles of the nuclear physics that on one hand aims at integrating all the scientific knowledge and on the other hand it aims at differentiating the scientific knowledge from techniques.

Considering physics, chemistry and biology as the foundation of the development and the differentiation of the scientific branches in computer science, I have examined the peculiar sciences that reflect the forms of the substance and its movement evolving in an inconsistent way. The inconsistent characteristic of nature development is revealed in the division of nature by phenomena that are both linked to natural factors, to the essence of the natural structure and to the nature of men and society. By the way, we can clearly explain the correlation between physics and chemistry and between the transitive sciences. This correlation directly reflects the connections between the elementary particles and the nucleus and between the atoms and the molecules. The movement of the elementary particles (protons, neutrons, positrons, electrons, eutons, hadrons, mesons, leptons and so on...) is part of the subatomic physics and the nuclear physics but the molecules forming the bodies are part of the molecular physics (superatomic). So, the way science is arranged corresponds to

The order of the development of the discrete forms of substance.        

Finality. Like the atoms, the  molecules  are  both part of chemistry and physics .As far as physics is concerned, the order of the development of the substance. Finally, like the atoms, the of chemistry and physics. As far as molecules are anything but a complex system and the result of the atomic interaction. As far as physics is concerned, molecules are initial "cells" producing the logical aggregates. From this epistemological viewpoint we respond to the advocates of the metaphysical monist approach praising an only science in the field of computer science. The basic issue of natural science is linked to the development of the philosophical thought and to the rapid progress of all the branches of the fundamental research that more and more integrate the fundamental natural science, technical science and even social science. This integration makes the transformative function of science increase the command of the natural forces and it changes science into a direct productive force. Finally it allows social science to improve and strengthen its organic connection with natural science.

The place of computer science within our sketch of science classification parts: natural science

First, I will divide science into two basic and human sciences.

1. Natural science:

- Physics, technique, mathematics - chemistry, technology, biology - earthly science

1) Physics, technique, computing and automation

Mathematics: Indeed, I consider as a physical, technological and mathematical science put into the first set of the natural science classification. Then, I will consider the classical science (the positive computer science, the computer science, the systematic and logical science) and the physical and technological computer analytical computer science (the methodological computer science and the applied computer science).

The contemporary computer science is divided into:

- The computerized management

- The computerized medicine

- The biocomputer science

- The computerized industry - robotics

- Telematics

- Telecomputers

- The scientific computer and the satellites computer science

- The nuclear computer science and astrophysics

I consider the mathematical science with its subdivisions (mathematics, physics, logical mathematics, applied mathematics and so on...) behind computer science. Finally I consider physics within the set of the physical, technical and mathematical science

1.3 Physics roughly speaking

1.4 Atomic, subatomic and superatomic physics

1.5 The nuclear physics

1.6 The physics on plasma 1.7 the quanta physics

1.8 The high energy physics 1.9 the basic particles physics 1.10 the contemporary physics (optics, spectroscopy, thermodynamics, the theory of magnetism, electricity, electronics, radio and radioactivity)

1.11 Mechanics (undulatory)

1.12 The physical and technical science of energy

1.13 The physical and technical science of mechanics and the control process (cybernetics and the management process)

2) Chemistry, technology, biology: First, I will divide chemistry into two main parts : the organic chemistry and the non organic chemistry. Then, following the analysis made page 323 of this research, I have made the following subdivisions: 2.1 chemistry and technics

2.2 The physical chemistry and the technology of the inorganic substances

2.3 biochemistry, biophysics, the chemistry of the active physiologic compounding (the chemistry of the complex compounding)

2.4 electrochemistry and radiochemistry 2.5 the chemical physics

2.6 The cinetical chemistry

2.7 Physiology

2.8 Biology and its subdivisions (microbiology, the molecular biology)

           2.9 The science of life: medicine and its scientific branches

3) The earthly science:

3.1 Geology

          3.2 Geophysics

        3.3 Geochemistry

3.4 Oceanography

3.5 The physics of the atmosphere20

3.6 The physics of the geography

2. Human sciences.

As far as human sciences are concerned we discern dialectics at the head of the philosophical science with several subdivisions: logics, epistemology, and esthetics. Then there are history, economy and law and finally literature and linguistics. They are the foundations of our classification. Human sciences are more important than any other science. They are based on the scientific rules that link natural sciences with philosophy and social sciences. Indeed before considering computing and automation as a physical, technical and mathematical science at the head of the first set of the natural sciences classification, it is advisable to tell about the metaphysical monist approach that defends the absolute unity of computer science and denies the division and the diversification of the scientific branches of computer science.

The historical approach first takes into account the relative development of computer technology that regards computer as a three dimension "discipline". The first computer science laid down the great inventions. It was little by main ideas going with the invention being different from cybernetics. The second computer science dates back to 1970's. It is characterized by the basic principles and little detached from the computer but without from the 1960's and the setting up of the great centralized systems. It was mainly made by opposition to a certain metaphysical cybernetics. According to this approach computer science will be automated and it will appear like the field especially dedicated to computers and their using. Thus it has become a technique to handle data whereas cybernetics used to ponder over the use of techniques in the modern world. The third computer science deals with the diversification of the means and methods, with the grids and the cohabitation between the small and large systems. Finally, this historical approach has neither a scientific objective nor a gnoseological or methodological one. It is not either a basic proof relating to the scientific and technical development.

Lastly, Ph. Dreyfus has divided computer science into 5 main fields. It is a positive approach but it remains in the classical apprehension of computer science:

a) The classical computer science and its subdivisions: 1. the positive computer science

2. The analytical computer science

3. The systematical and logical computer science

4. The physical and technological computer science

5. The methodological computer science

6. The applied computer science

1) The positive or analytical computer science is the nearest branch to the precise sciences. Computer science is not only diversified according to the object of the research and to the scientific division of labor but also according to its use within the working system.

2) The systematical and logical computer science looks into the architecture of the computerized systems in which the computers with their central processing unit, their memory and their data input and output step.

This classical and traditional approach of Dreyfus is far from looking at the process of the technological development of the systematical and logical computer science that has given rise to telecomputers, telematics, satellites computers and charts. According to Dreyfus there are connections between the physical and technological computer science and telecomputer

3) The physical and technological computer science is relatively out of date.

4) The methodological computer science refers to the research about programming. It has given rise to another scientific discipline from computer science: the artificial intelligence and the acknowledgement of shapes, the synthesis of voice, the engineering of knowledge.

5) The applied computer science enters the activities of the modern world.

The contemporary computer science is divided into: 1. the computerized management

2. The graphic computer science

3. The computerized medicine

4. The biocomputer science

5. The computerized industry

6. Robotics

7. Telematics

8. Telecomputers

9. The scientific computer technology and data processing relating to satellites

10. The nuclear computer science

The rise of the theoretical computer science is the main basis of this science on which computer science is rising. We can distinguish the theoretical computer science from the practical computer science. The difference comes either from inward in the theoretical logic either from outward in the applications. This second stage needs to specify the phenomena in order to set up the rule of the empirical foundations. The third stage is made of hypotheses. The scientific branches of computer technology as concrete aids to verify the hypotheses play a different part from the classical and traditional computer science and they enter into a new stage of the development, changing not only the argument but also the scientific applications of techniques.

As far as the scientific philosophy is concerned computer science is a technological science linked to the physical, technical and mathematical science. There is not an only computer science but several scientific branches linked both to the chemical, technological and biological sciences and to the earthly and human sciences. It is different from the classical computer science as far as the scientific ethics is concerned. From the dialectical analysis of computer technology we have introduced the classification of techniques that is no longer made according to the products but to the processes. For this classification we have used physics, chemistry and biology as bases for the diversification of the scientific branches of computer science and their connections within the sketch of the dialectical classification of science. The diversification of the scientific branches of computer science is due to military, economic, political and technological causes.

On one hand the application of data processing to the issue on defense has been of effect on the military strategy. And on the other hand, following their research into the "economic and social effects of the investments towards information" the Japanese have made evident the needs of the next informational society. And the traditional computer science cannot provide those needs. So, it has been necessary to think about different computerized systems. So, we will move directly from the third generation of computer to the fifth one.

The diversification is also economic: it deals with the output of hardware and its diversification within the process of production with respect to the needs in the competitive market. Pioneer from the local network and Ethernet, the American 3COM, has just carried out a great diversification while launching out into office automation. The firm has indeed decided to launch its own work stations especially made for the networks. It deals with a machine based on 80286 (usually it fits the PCs AT) and some suited circuits providing a 1M0 central memory extendible to 4M0 (...) The company deems its proposal is 30% to 50% cheaper than a classical solution with minicomputers and terminals. 3COM expects to sell 1200 stations in the world for the first year of marketing... But the world market of the local networks has difficulty in getting off the ground.



Nevertheless for the first 9 months the business has got a turnover of $79m (+76%) for a $8m net profit with an equal increase.

This state asserts that the radical change is not the result of abstract things; on the contrary everything proceeds from the material production and from the exploitation of the main wealth and the development of the labor force. The distinguished characteristic of technique as a commodity is not independent from the differentiation and the connection of capital and the originality of the diversification as a new technique. But this new technology is in opposition with the rules of the capital development. As a whole, the material basis of the production rules the differentiation and the variety of the scientific branches.

The diversification is also technical. "Technology is the science of the scientific and technical rules of the production process" What are these scientific and technical rules? What is their function within the production process in the technologically advanced societies where the productive human condition, their labor force, their social relations with foreign powers that lead them and crush them? Men become impotent, got off their social power defining by their international corporality, their so called "private" subjectiveness. So, within the computer process the system of the private appropriation of the collectively produced wealth unavoidably leads to the underdevelopment of the main wealth. What will the results of the scientific and technical revolution be in the new computerized society? How can we resolve the new problems posed by the new situation and to what extent can these universally developed technologies create the conditions for all individuals' growth? In reality the issue on men liberation is raised within a new conception of mankind. It is both the social and objective world in which we live as concrete individuals with our subjectiveness and the growth of the individuality. This individuality has no meaning except if mankind adapts itself to the whole of the external forces with which we have created our own aim. How can we secure men liberation from the direct production process after the control functions have been managed by automated systems? The liberation from the routine can both be a way of self-management in life and in the computerized society and a way of changing the productive basis into an automated system. Robotization provides a new content to the process not only to production but also to the social relationship. To what extent can computerization increase imployment, the importance of the cognitive and creative components in labor and to what extent can it improve the division of the scientific labor? In other words, how can we pose the issue on dialectics in the complete use of the intellectual potential of the human being and the computerized system for an harmonious combination between the artificial intellect in its improving and human thought? How can the unity of dialectics consisting in the division in two of one of them and the learning of these contradictory parts enrich mankind? How can know the unity of dialectics as a method that consists in identifying the contradictory tendencies enriches mankind? As far as the philosophy of the scientific revolutions is concerned the issue of the connection between philosophy and the scientific knowledge is raised from a dialectical analysis and a generalization of natural and human sciences. The methodological analysis of the scientific organization according to the discipline and from science classification is the main structural unity of science but on one hand science classification aims at integrating the scientific knowledge, their union and the discovery of their dialectical connections and on the other hand it aims the differentiation between the scientific and technological knowledge, their branching within the scientific knowledge because it gets several kinds of connections (communication, organization, reflection and so on...) At that stage we must resolve the scientific issue on the scientific organization and the philosophical foundations of computer science over three main levels.

Firstly a critic against the dogmatic position was absolutely useful in the scientific history. Then, this critical analysis has led to a new solution for numerous concrete issues on natural sciences as well as on human and technical sciences. It has clarified the way of the natural science development that embraces human sciences to realize an only science using technique to apply it in the productive system so that all the creative possibilities of technical sciences may be at the disposal of human sciences. In the computerized society the dialectical unity of science within an only science is a reality. This is the foundation of all sciences, the scientific and philosophical synthesis included. Indeed, this dialectical unity of the knowledge integration is not a melting of disciplines that have lost their identity but their interaction, their mutual enriching. So, we have been obliged to examine the object of science and especially the object of computer science as a physical, technical and mathematical science (a technologically unified science) in order to establish a system and a theory on science different from the subjective and objective idealism and to make evident the historical realization of an only science. On one hand the dialectical classification of science is the direct continuation of the French philosophers' science classification: d'Alembert, Diderot, Gassandi, Descartes, Saint Simon, A.Comte, A.M Ampere, A. Cournot. On the other hand we have raised the issue on the unity in the foundation of science classification, considering physics, chemistry and biology as the foundation of the basic sciences. As for computer science it is inseparable from the process of the scientific knowledge. But it seems that philosophy cannot play its part in an efficient way within the development of the world scientific conception as well as within the understanding of the philosophical foundation of computer science. Computer science has to emphasize itself among the other science that is to say as a cognitive and permanent activity with its own issue.

This social and ethical issue gets four main tendencies: first, science as a peculiar kind of human activity looks for the direct subject of this activity: human being. It is revealed when it becomes less and less socially alienated and more and more "humanly measurable" that is correlative with the qualities and needs of human being not only expressed in objective terms and social outcome but also in subjective qualities. This tendency is the result of a growing appreciation of the human activity. In other words science penetrates more pressingly the social life as well as the individual life. It changes it and it initiates rules and some new and unknown structures. It influences greatly the process: the human being becomes one of the main subjects of the scientific knowledge. Then, this tendency gets a clearer and direct socializations and humanization of the contemporary science included computer science when it reflects some more general processes linked to the need for a social and ethical regulation of science. So, science determines the creative and cognitive activity but this one gives science a new quality, a humanist trend which is quite important for the society and science itself. Without such a trend science and its application can become a dangerous and diabolical power used to destroy life on the Earth. The more science penetrates the mystery the more powerful men are. But its application involves liabilities. It raises the issue on the foundation of the scientific ethics and by the way on the philosophical liability of scientists. Through this issue we have pondered over the philosophical foundation of computer science.

Then, the need and the scientific nature of the science classification history has led us to suggest a new interpretation of the classification. The history of science classification needed such an explanation for two reasons: the first is that without raising the historical issue on the classification and without dealing with the issue on its change and on its manifestations in the various scientific fields and above all in computer science, it is impossible to raise the issue on the unity of the philosophical foundation of computer science. The second reason is that "science history deals with an axiological activity with the search after truth. It is at the stage of the issue on the method and the conception that the scientific activity as such appears. That is why the time of the science history can't be a side thread of the time course". So, on one hand according to us "science and culture consist in getting reality with them without getting drowned". And on the other hand we think that science proceeds from the need, the social activities of men with which they can change nature as well as themselves. By the way we can come to the issue on the structure of the scientific knowledge from the angle of the analysis of the conceptual system of science classification or computer science. For example in chemistry and physics, science was formed by itself and its object got specified parallel to the change in the former notions that were too vague in scientific concepts. We can note some phenomena in the other basic fields of the scientific knowledge. The process of formation of the basic sciences shows the general structure of the scientific knowledge. The structure can be the following: science roughly speaking as a sphere of activity for all the scientists; a peculiar branch of science (for example chemistry or physics); a narrow sphere of the scientific activity but independent from the scientist.

Finally the value of the existence of over five thousand millions human beings in a world full of fear and contradictions depends on the philosophical answers of our age. These philosophical answers give possibilities to science and to computer science and by multiplying discoveries and astonishing inventions that are able to provide a worthy life to all men. Philosophy and science do not lead to the whole negation of the main wealth, that is to say men themselves, because of a social system, but on the contrary they lead to the truth of the mankind existence that puts an end to all the trouble raised to men condition.

It is the part of science and philosophy. The scientific and technical revolution will release men from the automated production. There are some emancipative forces required to men. The problem is how to manage altogether these forces. This is the historic objective of the new humanism. It coincides with the growth of the competitive individualism as B. Brecht notes it: "climbing, always climbing over someone" whereas everybody can peacefully climb altogether.

This research is dedicated to the study of the classification of sciences and the philosophical foundations of computing to create the ACADEMY of   sciences and a national center for national research of Kurdistan . It concerns its logical, mathematical, linguistic, physical, technological and ethical aspects as a problem of the scientific philosophy of our century. An attempt is made to define the historical nature of the classification of sciences, to interpret its philosophical foundations and to specify its connections with the scientific and technical revolution from a philosophical and methodological point of view.

The dialectic analysis of the scientific knowledge of sciences and the philosophical foundations of computing is carried out on five different levels : the first corresponds to the study of all the processes aiming at developing the atomistic model of the classification and with the logical, mathematical, linguistic, physical, technological and ethical foundations of computing ; the second corresponds to some notions of the classification and organization of the scientific system of knowledge up to the fundamental principles of the development of knowledge and sciences; the third corresponds to the historical and scientific approaches of the classification of sciences and the fundamental principles of classification ; the fourth, to the classification of computing and the diversification of the scientific branches of computing (contemporary computing, management computing, graphical computing, medical computing, bio-computing, industrial computing, robotics, telematics and remote-access computing, etc.) ; finally the fifth one which is of highest level represents the general methodology of the philosophy of scientific revolutions which provides the whole structure of the scientific cognitive activity (artificial intelligence and scientific knowledge) and identifies the main types and mechanisms of the dialectics of the process of human knowledge. Consequently, particular attention is given to the revolution of computing, to society and to the method of treating science which makes it possible to show the contents of the Scientific and Technical revolution and to the place that computing occupies in the new outline of the dialectic classification of sciences. In the orientation of the philosophy of scientific revolutions, the socio ethical humanist and scientific approach shows four fundamental tendencies. Firstly, science as a particular form of human activity attempts to unite with itself the direct subject of this activity: man. Secondly, this tendency towards a clearer and more direct socializations and humanization of contemporary science, including computing, reflects more general processes linked with the need for a socio ethical and humanistic regulation of science. Thirdly, the need and the scientific nature of the history of the classification of sciences which obliges us to revalorize a new dialectic and materialistic interpretation of the classification. Fourthly, the question of the new civilization depends on the philosophical response of our time and the question of man's freedom which is posed in a new conception of humanity is both the social and objective world in which we live as concrete individuals, with our subjectivity, and the development of individuality which does not have any sense without the developed humanity that, by our appropriation of all these exterior forces, by which we have created our own end. By which means we can guarantee the liberation of man from the process of direct production following the handing over of the control and monitoring functions to the automatic, autoregulator systems or the liberation from routine work, its transformation into an act of creation in a technology that can become both an self management intervention and an instrument for men in everyday life and in the computerized firm ; it can become both an instrument for transforming productive bases into automatic systems, to the robotization that gives a new content to the process, not only in production but also in social responses. The answer can be given by the scientific philosophers to found the ACADEMY of  sciences and a national center for scientific research of Kurdistan


I think the new situation created by the possibility of the founding of our Academy offers us tremendous opportunities, but we also imposes important obligations. This brings me to ask you to the next question



What are the roles of an Academy of Sciences in a country like Kurdistan in the early 21st century? Why do the authorities of Kurdistan appeal to foreign countries without taking into account the academic potential of their country?



I think it is important that the authorities take into consideration the scientific functions structures in Kurdistan, the Kurdish purely science does not exist while the first function, which is also led to the creation of numerous academies to Throughout the world, is to provide scientific advice on matters that may arise citizens and their leaders. The benefits of an Academy of Sciences of Kurdistan are many on this plan: we gather the best expertise on most scientific issues. Like other academies, scientists Kurdistan could give their opinions either by scientific reports on the direction of economic policy in the country.

A second function of the Academy of Sciences Kurdistan is to contribute to the development of scientific knowledge. A third important function of the Academy of Sciences of Kurdistan is the representation of the science of Kurdistan within the international scientific world. Participate actively in the work of the International Union for Science (ICSU), the International Interacadémiques Councils (IAP / IAC) and the European Council of Academies. This council is new and its objective is to promote the understanding and support for Science

 

Dr Ali KILIC                                                 Paris  le 06-05-2008

 

Bibliographie

(i).François Dagognet L’ultime sanctuaire. In Milieux, W 30/1987, p.2

(2),Eftichios Bitsakis. Physique contemporaine et matérialisme dialectique

Editions Sociales, Paris, 1973, p.261-262

(3)N.Séménov. «La  philosophie  marxiste léniniste et les problèmes  des sciences naturelles  », In Le communiste, 1968, N°10, p.62-135

(4).A.Logounov . «Au coeur de la matière ’ Izvestia, le 22 décembre 1976.

(5) Koursanov,  Naouka i Jizn  N°7 p.8 1

(6), G,Frank ,L’opinion du savant ;. Moscou, Editions de 1’Acadmie des Sciences, 1963,p. 480

(7),G. Frank Opus. Cit..p .580

(8),P.. Thuillier, In  La Recherche Mai,l972.p.13

Editions du SeuiLParis,1975

(9). François Jacop  Biologie Moléculaire , In Atome 1969, In La recherche p.55

(10 ),F.Jacop,0pus.cit .p.58

(1l),V. Enguelgardt. Naouka j Jizn,1975,N° 5,p.II –

Jean Dominique Warnier, Homme face a 1'intelligence artificielle Les Editions d'Organisations, Paris,l984,p.19

Jean Claude Beaune, L'Automate et ses Mobiles Flammarion, Sciences Humaines, Paris, 1980,p.19

Karl Marx, Manuscrits 1844, Editions Sociales, Paris,1962, p.96

Hegel, Phenomenologie de 1'esprit, Tome,I,p.124

Hegel, Science de la Logique, Doctrine de 1'Essence, Tome,I Traduit de 1'alm.par J.P. Labariere et G. Jarzyk, Aubier,Paris,1976,p.91

J.C. Beaune, Technologie, PUF, Paris, 1972, p.8

Philippe Breton, Histoire de 1'informatique, p.127 Editions La Decouverte, Paris, 1987

Hegel, Science de la Logique, Doctrine de 1'Essence, Tome,I Traduit de 1'alm.par J.P. Labariere et G. Jarzyk, Aubier,Paris,1976,p.91

Florence Antomachi-A. Castiel-E. Seyden, Pense ... Machine Editions C.E.S.T.A.1986, p.144

Philippe Breton, Histoire de 1'informatique, p.127 Editions La Decouverte, Paris, 1987

Hegel, Science de la Logique, Doctrine de 1'Essence, Tome,I Traduit de 1'alm.par J.P. Labariere et G. Jarzyk, Aubier,Paris,1976,p.91

Informatique Magasine, Revue Pratique des PME-PMI Juin-aout 1987,N°9,p.16

Hirschfeld, Veda technika, Technologie,Prague,1963,p.259

 



[1] [1] Dr Ali KILIC,La Classification des Sciences  et l‘Informatique ; Fondements Philosophiques de l’Informatique, Publication de l’ Université Lille 1988, pp.313-330

 

[2] J.C Beaune. i.n Milieux, W 30,1987,p.76

[3] ibidem

[4] Eftichios  BITSAKIS. Physique  Contemporaine  et matérialisme dialectique,  Editions Sociales Paris ,1973,p.261-262

[5] ibid

[6] E. Séménov, La philosophie  marxiste léniniste   et les problèmes des sciences naturelles ; in le Communiste  1968, N° 10, p-62-135

[7] Koursanov,  Naouka i Jizn  N°7 p.8 1

[8] G,Frank,L’opinion du savant, Moscou , Editions de l’Académie des Sciences 1963, p.480

[9] G,Frank,Opus Cit. p.580

 

[10] P.. Thuillier, In  La Recherche Mai,l972.p.

 

[11] François Jacop, Biologie Moléculaire  In Atome, 1969, In La recherche  p.55

 

[12] F. Jacop, Opus Cit. .p ?58

[13] V. Enguelgardt, Naouka i Jizn 1975,N°5, p.11

[14] Denise Barlow (Vienne, Autriche)

[15] Bryan Turner (Birmingham, RU)

[16] Sarre, Allemagne

[17] Halle, Allemagne

[18] Peter Becker (Munich, Allemagne)

 

[19] Epigenetics and development

 

[20] Moshe YANIV Conférence débat et controverses « Epigénétique et mémoire cellulaire,

une nouvelle discipline, au cœur du développement et des pathologies »

 

[21] Centre Wellcome Trust pour la biologie cellulaire, Edimbourg, GB

 

[22] Adrian BIRD, Institute of Cell Biology, University of Edinburgh, UK The Wellcome Trust Centre for Cell Biology, University ofEdinburgh, Michael

[23] Conférence débat et controverses Epigénétique et mémoire cellulaire, une nouvelle discipline, au cœur du développement et des pathologie

 

 

[24] Robert FEIL, Institut de Génétique Moléculaire, Montpellier L’empreinte génomique et son rôle dans le développement Robert Feil, Institut de Génétique Moléculaire (IGMM), CNRS et Université de Montpellier,

 

 

[25] , Institut de Génétique Humaine , Montpellier

[26] Giacomo CAVALLI, Epîgénétique et développement,  Institut de Génétique Humaine, Montpellier

 

[27] Université de Nice-Sophia Antipolis

 

[28] References

Chandler, V. L. (2007). Paramutation: RNA-mediated instructions passed

across generations. Cell 23, 641-645.

Herman, H., Lu, M., Anggraini, M., Sikora, A., Chang, Y., Yoon, B. J., et

Soloway, P. D. (2003). Transallele methylation and paramutation-like

effects in mice. Nat Genet 34, 199-202.

Rassoulzadegan, M., Magliano, M., et Cuzin, F. (2002). Transvection

effects involving DNA methylation during meiosis in the mouse. Embo J 21,

440-450.

Rassoulzadegan, M., Grandjean, V., Gounon, P., Vincent, S., Gillot, I., et

Cuzin, F. (2006). RNA-mediated non-Mendelian inheritance of an

epigenetic change in the mouse. Nature 431, 469-474.

Wagner, K. D., Wagner, N., Ghanbarian, H., Grandjean, V., Gounon, P.,

Cuzin, F., et Rassoulzadegan, M. (2008). RNA induction and inheritance of

epigenetic cardiac hypertrophy in the mouse. Dev Cell, sous presse.

 

[29] [29] Institut de Génétique Humaine, CNRS, Montpellier, France

 

[30] Institut Pasteur, Paris

[31] [31] References

1. Brink, R. A. Genetics 1956, 41, 872-879.

2. Chandler, V. L. & Stam, M. Nat Rev Genet 2004, 5, 532-44.

3. Rassoulzadegan, M. et al. 2002 EMBO J, 21, 440-450.

4. Rassoulzadegan, M. et al. Nature 2006, 431, 469-474.

5. Wagner et al., Dev Cell 2008, in press.

6. Miller, D., Ostermeier, G. C. & Krawetz, S. A. Trends Mol Med 2005,

11, 156-63.

 

 

 

 

print

copyright © 2002-2005 info@pen-kurd.org